Needle-Free PRP Alternative: Alma TED+ Transepidermal Delivery for Hair Restoration
Dr. Steven Hopping, a board-certified hair restoration surgeon, is now offering a revolutionary needle-free treatment for hair thinning using the Alma TED (Transepidermal Delivery) system combined with a specialized serum called TED+.
This advanced treatment delivers powerful growth factors, peptides, and proteins directly to the hair follicles without any injections, making it a comfortable and effective option for patients seeking thicker, healthier hair.
The Science Behind TED+ Serum
The TED+ serum is a clinically formulated, high-potency blend containing over 30 active ingredients. While the exact proprietary ratio is a trade secret, the formula focuses on key growth factors and signaling molecules that target hair thinning and scalp health:
1. Vascular Endothelial Growth Factor (VEGF)
One of the most important proteins in the serum. VEGF stimulates angiogenesis (new blood vessel formation), dramatically improving microcirculation around the hair follicle. Better blood flow means more oxygen and nutrients, helping hair stay in the active growth phase (anagen) longer.
2. Fibroblast Growth Factors (FGF)
These essential proteins signal cells in the hair bulb to transition from the resting phase (telogen) back into the active growth phase (anagen), promoting new hair growth and follicle revitalization.
3. Transforming Growth Factor-Beta (TGF-β)
Specific isoforms in the serum act as “traffic controllers” for the hair cycle. They help regulate signaling pathways to prevent premature follicle miniaturization and maintain healthy hair density.
4. Hepatocyte Growth Factor (HGF)
A powerful stimulator of hair follicle growth. HGF works synergistically with other proteins to increase follicle size, resulting in visibly thicker and stronger hair shafts.
5. Specialized Polypeptides & Signal Peptides
In addition to the larger growth factors, the serum contains targeted, smaller peptides that provide multiple benefits:
Collagen Stimulation – Strengthens the connective tissue that anchors the hair
DHT Modulation – Creates a scalp environment less favorable to thinning-causing hormones
Inflammation Reduction – Calms the scalp and reduces stress on the follicles
How It Works: Needle-Free Delivery
Large protein and growth factor molecules are normally too big to penetrate the skin on their own.
The Alma TED device solves this using sonophoresis — a patented combination of acoustic sound waves and air pressure. These gentle energy waves temporarily open micro-channels in the skin’s lipid barrier, allowing the TED+ serum to reach the bulb of the hair follicle effectively — all without needles.


